Bloody Diarrhea
Fewer than 1% of Accutane® users develop bloody diarrhea. Notify of your doctor before starting Accutane® if you have ever had blood in your stool, any unaccounted GI symptoms or a history of ulcerative colitis or Crohn’s disease (inflammatory bowel disease). Notify your doctor if you develop bleeding from the rectum, bloody diarrhea or any persistent unusual GI symptoms during Accutane® treatment.